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GWAS 2024-05-14

Common variation in a long non-coding RNA gene modulates variation of circulating TGF-β2 levels in metastatic colorectal cancer patients (Alliance).

Quintanilha JCF, Sibley AB et al.

BMC Genomics

Herein, we report results from a genome-wide study conducted to identify protein quantitative trait ...

Angiopoietin-2 levels in metastatic colorectal cancer

869

Participants

N/A

Studies

Details PubMed

GWAS 2024-04-25

Germline genetic regulation of the colorectal tumor immune microenvironment.

Schmit SL, Tsai YY et al.

BMC Genomics

Objective: To evaluate the contribution of germline genetics to regulating the briskness and diversi...

T-cell receptor abundance in colorectal cancer

Replicated

2651

Participants

N/A

Studies

Details PubMed

GWAS 2024-03-07

Genome-wide association studies highlight novel risk loci for septal defects and left-sided congenital heart defects.

Broberg M, Ampuja M et al.

BMC Genomics

Congenital heart defects (CHD) are structural defects of the heart affecting approximately 1% of new...

Congenital heart defects

Replicated

882963

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-26

Body mass index stratified meta-analysis of genome-wide association studies of polycystic ovary syndrome in women of European ancestry.

Burns K, Mullin BH et al.

BMC Genomics

Polycystic ovary syndrome (PCOS) is a complex multifactorial disorder with a substantial genetic com...

Polycystic ovary syndrome in lean individuals (BMI <= 25 kg/m2)

119584

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-08

Sex-biased genetic regulation of inflammatory proteins in the Dutch population.

Boahen CK, Abee H et al.

BMC Genomics

Significant differences in immune responses, prevalence or susceptibility of diseases and treatment ...

CXCL9 levels

318

Participants

N/A

Studies

Details PubMed

GWAS 2024-01-10

Polygenic risk score model for renal cell carcinoma in the Korean population and relationship with lifestyle-associated factors.

Hong JY, Han JH et al.

BMC Genomics

The polygenic risk score (PRS) is used to predict the risk of developing common complex diseases or ...

Renal cell carcinoma

4423

Participants

N/A

Studies

Details PubMed

GWAS 2022-12-19

Genome-wide association study identifies novel loci associated with skin autofluorescence in individuals without diabetes.

Vollenbrock CE, Roshandel D et al.

BMC Genomics

Skin autofluorescence (SAF) is a non-invasive measure reflecting accumulation of advanced glycation ...

Skin autofluorescence

27254

Participants

N/A

Studies

Details PubMed

GWAS 2022-09-27

Genome-wide association analyses of common infections in a large practice-based biobank.

Jiang L, Kerchberger VE et al.

BMC Genomics

Introduction: Infectious diseases are common causes of morbidity and mortality worldwide. Susceptibi...

Otitis media

14604

Participants

N/A

Studies

Details PubMed

GWAS 2022-04-04

Identification and functional validation of HLA-C as a potential gene involved in colorectal cancer in the Korean population.

Lim EB, Oh HS et al.

BMC Genomics

Colorectal cancer (CRC) is the third most common cancer worldwide and is influenced by environmental...

Colorectal cancer

794

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-23

Sex-specific genetic modifiers identified susceptibility of cold stored red blood cells to osmotic hemolysis.

Fang F, Hazegh K et al.

BMC Genomics

Genetic variants have been found to influence red blood cell (RBC) susceptibility to hemolytic stres...

Osmotic hemolysis of cold stored red blood cells

6128

Participants

N/A

Studies

Details PubMed

GWAS 2022-01-28

Genome-Wide association study of quantitative biomarkers identifies a novel locus for alzheimer's disease at 12p12.1.

Lee B, Yao X et al.

BMC Genomics

Genetic study of quantitative biomarkers in Alzheimer's Disease (AD) is a promising method to identi...

Rey auditory verbal learning test (24 month visit)

1576

Participants

N/A

Studies

Details PubMed

GWAS 2021-06-09

Multi-ethnic genome-wide association analyses of white blood cell and platelet traits in the Population Architecture using Genomics and Epidemiology (PAGE) study.

Hu Y, Bien SA et al.

BMC Genomics

Circulating white blood cell and platelet traits are clinically linked to various disease outcomes a...

White blood cell count (basophil)

Replicated

27236

Participants

N/A

Studies

Details PubMed

Title

Author

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Disease/Trait

Date

Actions

Common variation in a long non-coding RNA gene modulates variation of circulating TGF-β2 levels in metastatic colorectal cancer patients (Alliance).

Quintanilha JCF, Sibley AB et al.

BMC Genomics

Angiopoietin-2 levels in metastatic colorectal cancer

2024-05-14

Germline genetic regulation of the colorectal tumor immune microenvironment.

Schmit SL, Tsai YY et al.

BMC Genomics

T-cell receptor abundance in colorectal cancer

2024-04-25

Genome-wide association studies highlight novel risk loci for septal defects and left-sided congenital heart defects.

Broberg M, Ampuja M et al.

BMC Genomics

Congenital heart defects

2024-03-07

Body mass index stratified meta-analysis of genome-wide association studies of polycystic ovary syndrome in women of European ancestry.

Burns K, Mullin BH et al.

BMC Genomics

Polycystic ovary syndrome in lean individuals (BMI <= 25 kg/m2)

2024-02-26

Sex-biased genetic regulation of inflammatory proteins in the Dutch population.

Boahen CK, Abee H et al.

BMC Genomics

CXCL9 levels

2024-02-08

Polygenic risk score model for renal cell carcinoma in the Korean population and relationship with lifestyle-associated factors.

Hong JY, Han JH et al.

BMC Genomics

Renal cell carcinoma

2024-01-10

Genome-wide association study identifies novel loci associated with skin autofluorescence in individuals without diabetes.

Vollenbrock CE, Roshandel D et al.

BMC Genomics

Skin autofluorescence

2022-12-19

Genome-wide association analyses of common infections in a large practice-based biobank.

Jiang L, Kerchberger VE et al.

BMC Genomics

Otitis media

2022-09-27

Identification and functional validation of HLA-C as a potential gene involved in colorectal cancer in the Korean population.

Lim EB, Oh HS et al.

BMC Genomics

Colorectal cancer

2022-04-04

Sex-specific genetic modifiers identified susceptibility of cold stored red blood cells to osmotic hemolysis.

Fang F, Hazegh K et al.

BMC Genomics

Osmotic hemolysis of cold stored red blood cells

2022-03-23

Genome-Wide association study of quantitative biomarkers identifies a novel locus for alzheimer's disease at 12p12.1.

Lee B, Yao X et al.

BMC Genomics

Rey auditory verbal learning test (24 month visit)

2022-01-28

Multi-ethnic genome-wide association analyses of white blood cell and platelet traits in the Population Architecture using Genomics and Epidemiology (PAGE) study.

Hu Y, Bien SA et al.

BMC Genomics

White blood cell count (basophil)

2021-06-09