Active: Hum Genomics Clear all

GWAS 2024-06-11

Shared genetic effect of kidney function on bipolar and major depressive disorders: a large-scale genome-wide cross-trait analysis.

Yu S, Lin Y et al.

Hum Genomics

Epidemiological studies have revealed a significant association between impaired kidney function and...

Bipolar disorder or blood urea nitrogen levels (MTAG)

904388

Participants

N/A

Studies

Details PubMed

GWAS 2024-03-15

A genome-wide association study of neutrophil count in individuals associated to an African continental ancestry group facilitates studies of malaria pathogenesis.

Constantinescu AE, Hughes DA et al.

Hum Genomics

'Benign ethnic neutropenia' (BEN) is a heritable condition characterized by lower neutrophil counts,...

Neutrophil count

5976

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-10

Genetic basis of STEM occupational choice and regional economic performance: a UK biobank genome-wide association study.

Zhu C, Zhao Q et al.

Hum Genomics

Science, technology, engineering, and mathematics (STEM) professionals are regarded as the highly sk...

Science, technology, engineering or mathematics occupational choice

178976

Participants

N/A

Studies

Details PubMed

GWAS 2022-12-08

Comprehensive characterization of putative genetic influences on plasma metabolome in a pediatric cohort.

Lee IH, Smith MR et al.

Hum Genomics

The human exposome is composed of diverse metabolites and small chemical compounds originated from e...

Plasma metabolome feature (c18_403)

441

Participants

N/A

Studies

Details PubMed

GWAS 2022-10-21

Nidogen-1 could play a role in diabetic kidney disease development in type 2 diabetes: a genome-wide association meta-analysis.

Khattab A, Torkamani A

Hum Genomics

Diabetic kidney disease (DKD) affects about 40% of patients with diabetes. It is incurable and usual...

Diabetic kidney disease in type 2 diabetes

13123

Participants

N/A

Studies

Details PubMed

GWAS 2021-02-03

Genetic variants are identified to increase risk of COVID-19 related mortality from UK Biobank data.

Hu J, Li C et al.

Hum Genomics

The severity of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome ...

Mortality in COVID-19

1096

Participants

N/A

Studies

Details PubMed

GWAS 2020-09-14

Long non-coding RNA MIR4300HG polymorphisms are associated with postoperative nausea and vomiting: a genome-wide association study.

Sugino S, Konno D et al.

Hum Genomics

Genetic factors such as single-nucleotide polymorphisms (SNPs) play a key role in the development of...

Postoperative nausea and vomiting

Replicated

256

Participants

N/A

Studies

Details PubMed

GWAS 2019-06-13

Genome-wide enriched pathway analysis of acute post-radiotherapy pain in breast cancer patients: a prospective cohort study.

Lee E, Takita C et al.

Hum Genomics

Adjuvant radiotherapy (RT) can increase the risk of developing pain; however, the molecular mechanis...

Acute post-radiotherapy pain in breast cancer

1112

Participants

N/A

Studies

Details PubMed

GWAS 2019-05-21

Genetics of heart rate in heart failure patients (GenHRate).

Evans KL, Wirtz HS et al.

Hum Genomics

Elevated resting heart rate (HR) is a risk factor and therapeutic target in patients with heart fail...

Heart rate in heart failure with reduced ejection fraction

1043

Participants

N/A

Studies

Details PubMed

GWAS 2019-05-15

Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans.

Guan M, Keaton JM et al.

Hum Genomics

End-stage kidney disease (ESKD) is a significant public health concern disproportionately affecting ...

Type 2 diabetes and end-stage kidney disease

10409

Participants

N/A

Studies

Details PubMed

GWAS 2019-01-31

A genome-wide association study of mitochondrial DNA copy number in two population-based cohorts.

Guyatt AL, Brennan RR et al.

Hum Genomics

Mitochondrial DNA copy number (mtDNA CN) exhibits interindividual and intercellular variation, but f...

Mitochondrial DNA copy number (white blood cells)

1333

Participants

N/A

Studies

Details PubMed

GWAS 2018-11-01

Multiple genotype-phenotype association study reveals intronic variant pair on SIDT2 associated with metabolic syndrome in a Korean population.

Moon S, Lee Y et al.

Hum Genomics

Metabolic syndrome is a risk factor for type 2 diabetes and cardiovascular disease. We identified co...

Metabolic syndrome

Replicated

10036

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Shared genetic effect of kidney function on bipolar and major depressive disorders: a large-scale genome-wide cross-trait analysis.

Yu S, Lin Y et al.

Hum Genomics

Bipolar disorder or blood urea nitrogen levels (MTAG)

2024-06-11

A genome-wide association study of neutrophil count in individuals associated to an African continental ancestry group facilitates studies of malaria pathogenesis.

Constantinescu AE, Hughes DA et al.

Hum Genomics

Neutrophil count

2024-03-15

Genetic basis of STEM occupational choice and regional economic performance: a UK biobank genome-wide association study.

Zhu C, Zhao Q et al.

Hum Genomics

Science, technology, engineering or mathematics occupational choice

2023-05-10

Comprehensive characterization of putative genetic influences on plasma metabolome in a pediatric cohort.

Lee IH, Smith MR et al.

Hum Genomics

Plasma metabolome feature (c18_403)

2022-12-08

Nidogen-1 could play a role in diabetic kidney disease development in type 2 diabetes: a genome-wide association meta-analysis.

Khattab A, Torkamani A

Hum Genomics

Diabetic kidney disease in type 2 diabetes

2022-10-21

Genetic variants are identified to increase risk of COVID-19 related mortality from UK Biobank data.

Hu J, Li C et al.

Hum Genomics

Mortality in COVID-19

2021-02-03

Long non-coding RNA MIR4300HG polymorphisms are associated with postoperative nausea and vomiting: a genome-wide association study.

Sugino S, Konno D et al.

Hum Genomics

Postoperative nausea and vomiting

2020-09-14

Genome-wide enriched pathway analysis of acute post-radiotherapy pain in breast cancer patients: a prospective cohort study.

Lee E, Takita C et al.

Hum Genomics

Acute post-radiotherapy pain in breast cancer

2019-06-13

Genetics of heart rate in heart failure patients (GenHRate).

Evans KL, Wirtz HS et al.

Hum Genomics

Heart rate in heart failure with reduced ejection fraction

2019-05-21

Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans.

Guan M, Keaton JM et al.

Hum Genomics

Type 2 diabetes and end-stage kidney disease

2019-05-15

A genome-wide association study of mitochondrial DNA copy number in two population-based cohorts.

Guyatt AL, Brennan RR et al.

Hum Genomics

Mitochondrial DNA copy number (white blood cells)

2019-01-31

Multiple genotype-phenotype association study reveals intronic variant pair on SIDT2 associated with metabolic syndrome in a Korean population.

Moon S, Lee Y et al.

Hum Genomics

Metabolic syndrome

2018-11-01