Active: J Med Genet Clear all

GWAS 2023-10-27

Functional annotation with expression validation identifies novel metastasis-relevant genes from post-GWAS risk loci in sporadic colorectal carcinomas.

Thean LF, Wong M et al.

J Med Genet

Colorectal cancer (CRC) is the third highest incidence cancer and is the leading cause of cancer mor...

Colorectal cancer (metastasis vs no metastasis)

Replicated

3514

Participants

N/A

Studies

Details PubMed

GWAS 2019-06-19

Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in Finns.

Sliz E, Kalaoja M et al.

J Med Genet

Inflammatory processes contribute to the pathophysiology of multiple chronic conditions. Genetic fac...

Soluble E-selectin levels

5284

Participants

N/A

Studies

Details PubMed

GWAS 2019-04-17

Multivariate genome-wide association study of rapid automatised naming and rapid alternating stimulus in Hispanic American and African-American youth.

Truong DT, Adams AK et al.

J Med Genet

Rapid automatised naming (RAN) and rapid alternating stimulus (RAS) are reliable predictors of readi...

Latent naming speed

441

Participants

N/A

Studies

Details PubMed

GWAS 2019-02-26

Genome-wide meta-analysis identifies genetic locus on chromosome 9 associated with Modic changes.

Freidin M, Kraatari M et al.

J Med Genet

Low back pain (LBP) is a common disabling condition. Lumbar disc degeneration (LDD) may be a contrib...

Modic changes

1829

Participants

N/A

Studies

Details PubMed

GWAS 2018-09-28

Common variants at 5q33.1 predispose to migraine in African-American children.

Chang X, Pellegrino R et al.

J Med Genet

Genome-wide association studies (GWASs) have identified multiple susceptibility loci for migraine in...

Paediatric migraine

Replicated

14706

Participants

N/A

Studies

Details PubMed

GWAS 2018-08-30

Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort.

Galván-Femenía I, Obón-Santacana M et al.

J Med Genet

Heritability estimates have revealed an important contribution of SNP variants for most common trait...

Anthropometric traits (multi-trait analysis)

Replicated

341095

Participants

N/A

Studies

Details PubMed

GWAS 2018-03-07

Multiplex genomewide association analysis of breast milk fatty acid composition extends the phenotypic association and potential selection of FADS1 variants to arachidonic acid, a critical infant micronutrient.

Mychaleckyj JC, Nayak U et al.

J Med Genet

Breast milk is the sole nutrition source during exclusive breastfeeding, and polyunsaturated fatty a...

Breast milk fatty acid composition (maternal genotype effect)

1142

Participants

N/A

Studies

Details PubMed

GWAS 2018-02-16

Genome-wide association study identifies ERBB4 on 2q34 as a novel locus associated with sperm motility in Japanese men.

Sato Y, Tajima A et al.

J Med Genet

The decrease in sperm motility has a potent influence on fertilisation. Sperm motility, represented ...

Sperm motility

Replicated

1590

Participants

N/A

Studies

Details PubMed

GWAS 2017-11-18

Genome-wide association study of telomere length among South Asians identifies a second RTEL1 association signal.

Delgado DA, Zhang C et al.

J Med Genet

Leucocyte telomere length (TL) is a potential biomarker of ageing and risk for age-related disease. ...

Telomere length

5075

Participants

N/A

Studies

Details PubMed

GWAS 2017-10-10

GWAS on prolonged gestation (post-term birth): analysis of successive Finnish birth cohorts.

Schierding W, Antony J et al.

J Med Genet

Gestation is a crucial timepoint in human development. Deviation from a term gestational age correla...

Post-term birth

4792

Participants

N/A

Studies

Details PubMed

GWAS 2016-12-30

A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.

Noordam R, Sitlani CM et al.

J Med Genet

Increased heart rate and a prolonged QT interval are important risk factors for cardiovascular morbi...

QT interval (tricyclic/tetracyclic antidepressant use interaction)

121935

Participants

N/A

Studies

Details PubMed

GWAS 2016-12-09

Genome-wide association study identifies variants in HORMAD2 associated with tonsillectomy.

Feenstra B, Bager P et al.

J Med Genet

Inflammation of the tonsils is a normal response to infection, but some individuals experience recur...

Tonsillectomy

Replicated

16425

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Functional annotation with expression validation identifies novel metastasis-relevant genes from post-GWAS risk loci in sporadic colorectal carcinomas.

Thean LF, Wong M et al.

J Med Genet

Colorectal cancer (metastasis vs no metastasis)

2023-10-27

Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in Finns.

Sliz E, Kalaoja M et al.

J Med Genet

Soluble E-selectin levels

2019-06-19

Multivariate genome-wide association study of rapid automatised naming and rapid alternating stimulus in Hispanic American and African-American youth.

Truong DT, Adams AK et al.

J Med Genet

Latent naming speed

2019-04-17

Genome-wide meta-analysis identifies genetic locus on chromosome 9 associated with Modic changes.

Freidin M, Kraatari M et al.

J Med Genet

Modic changes

2019-02-26

Common variants at 5q33.1 predispose to migraine in African-American children.

Chang X, Pellegrino R et al.

J Med Genet

Paediatric migraine

2018-09-28

Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort.

Galván-Femenía I, Obón-Santacana M et al.

J Med Genet

Anthropometric traits (multi-trait analysis)

2018-08-30

Multiplex genomewide association analysis of breast milk fatty acid composition extends the phenotypic association and potential selection of FADS1 variants to arachidonic acid, a critical infant micronutrient.

Mychaleckyj JC, Nayak U et al.

J Med Genet

Breast milk fatty acid composition (maternal genotype effect)

2018-03-07

Genome-wide association study identifies ERBB4 on 2q34 as a novel locus associated with sperm motility in Japanese men.

Sato Y, Tajima A et al.

J Med Genet

Sperm motility

2018-02-16

Genome-wide association study of telomere length among South Asians identifies a second RTEL1 association signal.

Delgado DA, Zhang C et al.

J Med Genet

Telomere length

2017-11-18

GWAS on prolonged gestation (post-term birth): analysis of successive Finnish birth cohorts.

Schierding W, Antony J et al.

J Med Genet

Post-term birth

2017-10-10

A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.

Noordam R, Sitlani CM et al.

J Med Genet

QT interval (tricyclic/tetracyclic antidepressant use interaction)

2016-12-30

Genome-wide association study identifies variants in HORMAD2 associated with tonsillectomy.

Feenstra B, Bager P et al.

J Med Genet

Tonsillectomy

2016-12-09