Active: Psychol Med Clear all

GWAS 2023-05-23

Investigating the shared genetic architecture of post-traumatic stress disorder and gastrointestinal tract disorders: a genome-wide cross-trait analysis.

Zhou S, Luo H et al.

Psychol Med

Observational studies suggest a correlation between post-traumatic stress disorder (PTSD) and gastro...

Post-traumatic stress disorder (MTAG)

174659

Participants

N/A

Studies

Details PubMed

GWAS 2021-12-06

Shared genetic influences on depression and menopause symptoms.

Meijsen JJ, Shen H et al.

Psychol Med

Women experience major depression and post-traumatic stress disorder (PTSD) approximately twice as o...

Medication use (estrogens)

232993

Participants

N/A

Studies

Details PubMed

GWAS 2020-08-07

Genetic correlation, pleiotropy, and causal associations between substance use and psychiatric disorder.

Jang SK, Saunders G et al.

Psychol Med

Substance use occurs at a high rate in persons with a psychiatric disorder. Genetically informative ...

Substance uses or psychiatric disorders (pleiotropy)

3163885

Participants

N/A

Studies

Details PubMed

GWAS 2019-11-06

Evidence for causal effects of lifetime smoking on risk for depression and schizophrenia: a Mendelian randomisation study.

Wootton RE, Richmond RC et al.

Psychol Med

Smoking prevalence is higher amongst individuals with schizophrenia and depression compared with the...

Lifetime smoking index

462690

Participants

N/A

Studies

Details PubMed

GWAS 2019-09-18

Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9.

Thorp JG, Marees AT et al.

Psychol Med

Depression is a clinically heterogeneous disorder. Previous large-scale genetic studies of depressio...

Depressive symptom (depressed mood) (binary trait)

148752

Participants

N/A

Studies

Details PubMed

GWAS 2019-06-03

Dentate gyrus volume deficit in schizophrenia.

Nakahara S, Turner JA et al.

Psychol Med

Schizophrenia is associated with robust hippocampal volume deficits but subregion volume deficits, t...

Dentate gyrus volume x schizophrenia interaction

275

Participants

N/A

Studies

Details PubMed

GWAS 2016-03-21

Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies.

Demirkan A, Lahti J et al.

Psychol Med

Major depressive disorder (MDD) is moderately heritable, however genome-wide association studies (GW...

Depressive symptoms measurement (somatic complaints domain)

Replicated

39341

Participants

N/A

Studies

Details PubMed

GWAS 2012-12-14

Estimating the heritability of reporting stressful life events captured by common genetic variants.

Power RA, Wingenbach T et al.

Psychol Med

Although usually thought of as external environmental stressors, a significant heritable component h...

Reporting of stressful life event

Replicated

3729

Participants

N/A

Studies

Details PubMed

GWAS 2011-11-01

Pharmacogenomic study of side-effects for antidepressant treatment options in STAR*D.

Clark SL, Adkins DE et al.

Psychol Med

Understanding individual differences in susceptibility to antidepressant therapy side-effects is ess...

Response to anti-depressant treatment in major depressive disorder

1439

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Investigating the shared genetic architecture of post-traumatic stress disorder and gastrointestinal tract disorders: a genome-wide cross-trait analysis.

Zhou S, Luo H et al.

Psychol Med

Post-traumatic stress disorder (MTAG)

2023-05-23

Shared genetic influences on depression and menopause symptoms.

Meijsen JJ, Shen H et al.

Psychol Med

Medication use (estrogens)

2021-12-06

Genetic correlation, pleiotropy, and causal associations between substance use and psychiatric disorder.

Jang SK, Saunders G et al.

Psychol Med

Substance uses or psychiatric disorders (pleiotropy)

2020-08-07

Evidence for causal effects of lifetime smoking on risk for depression and schizophrenia: a Mendelian randomisation study.

Wootton RE, Richmond RC et al.

Psychol Med

Lifetime smoking index

2019-11-06

Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9.

Thorp JG, Marees AT et al.

Psychol Med

Depressive symptom (depressed mood) (binary trait)

2019-09-18

Dentate gyrus volume deficit in schizophrenia.

Nakahara S, Turner JA et al.

Psychol Med

Dentate gyrus volume x schizophrenia interaction

2019-06-03

Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies.

Demirkan A, Lahti J et al.

Psychol Med

Depressive symptoms measurement (somatic complaints domain)

2016-03-21

Estimating the heritability of reporting stressful life events captured by common genetic variants.

Power RA, Wingenbach T et al.

Psychol Med

Reporting of stressful life event

2012-12-14

Pharmacogenomic study of side-effects for antidepressant treatment options in STAR*D.

Clark SL, Adkins DE et al.

Psychol Med

Response to anti-depressant treatment in major depressive disorder

2011-11-01