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GWAS Study

Cross-genetic determination of maternal and neonatal immune mediators during pregnancy.

Traglia M, Croen LA, Jones KL et al.

30134952 PubMed ID
GWAS Study Type
790 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

TM
Traglia M
CL
Croen LA
JK
Jones KL
HL
Heuer LS
YR
Yolken R
KM
Kharrazi M
DG
DeLorenze GN
AP
Ashwood P
VD
Van de Water J
WL
Weiss LA
Chapter II

Abstract

Summary of the research findings

The immune system plays a fundamental role in development during pregnancy and early life. Alterations in circulating maternal and neonatal immune mediators have been associated with pregnancy complications as well as susceptibility to autoimmune and neurodevelopmental conditions in later life. Evidence suggests that the immune system in adults not only responds to environmental stimulation but is also under strong genetic control.

790 Hispanic, European, Asian, South Asian or African American individuals

Chapter III

Study Statistics

Key metrics and study information

790
Total Participants
GWAS
Study Type
No
Replicated
European, South Asian, Asian unspecified, African American or Afro-Caribbean, Hispanic or Latin American
Ancestry
U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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