Active: Atopic dermatitis Clear all

GWAS 2025-04-01

Integration of GWAS, QTLs and keratinocyte functional assays reveals molecular mechanisms of atopic dermatitis.

Oliva M, Sarkar MK et al.

Nat Commun

Atopic dermatitis is a highly heritable and common inflammatory skin condition affecting children an...

Atopic dermatitis

658426

Participants

N/A

Studies

Details PubMed

GWAS 2024-11-15

A genome-wide cross-trait analysis identifying shared genetic basis and causal relationships between Hunner-type interstitial cystitis and autoimmune diseases in East Asian populations.

Lyu X, Peng L et al.

Front Immunol

Purpose: Epidemiological studies have demonstrated the clinical link between Hunner interstitial cys...

Hunner-type interstitial cystitis or atopic dermatitis (MTAG)

190904

Participants

N/A

Studies

Details PubMed

GWAS 2024-09-07

Joint genotype and ancestry analysis identify novel loci associated with atopic dermatitis in African American population.

Gautam Y, Satish L et al.

HGG Adv

Atopic dermatitis (AD) is a chronic itchy inflammatory disease of the skin. Genetic studies have ide...

Atopic dermatitis

1725

Participants

N/A

Studies

Details PubMed

GWAS 2024-04-23

Identifying atopic dermatitis risk loci in 1,094,060 individuals with sub analysis of disease severity and onset.

Pasanen A, Sliz E et al.

J Invest Dermatol

Atopic dermatitis (AD) is a common inflammatory skin disease highly attributable to genetic factors....

Atopic dermatitis

1094060

Participants

N/A

Studies

Details PubMed

GWAS 2024-04-01

Genome-wide Association Study of Susceptibility Loci for Self-Reported Atopic Dermatitis and Allergic Rhinitis in the Korean Population.

Kim JW, Kim MJ et al.

Ann Dermatol

Allergic diseases include atopic dermatitis (AD) and allergic rhinitis (AR), which are chronic, rela...

Allergic disease

8823

Participants

N/A

Studies

Details PubMed

GWAS 2024-01-08

The genome-wide association study of serum IgE levels demonstrated the shared genetic background in allergic diseases.

Lu HF, Chou CH et al.

Clin Immunol

Immunoglobulin E (IgE) synthessis is highly related to a variety of atopic diseases, and several gen...

Serum IgE levels

Replicated

17884

Participants

N/A

Studies

Details PubMed

GWAS 2023-10-04

European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.

Budu-Aggrey A, Kilanowski A et al.

Nat Commun

Atopic dermatitis (AD) is a common inflammatory skin condition and prior genome-wide association stu...

Atopic dermatitis

Replicated

4690421

Participants

N/A

Studies

Details PubMed

GWAS 2023-01-18

Inflammatory and infectious upper respiratory diseases associate with 41 genomic loci and type 2 inflammation.

Saarentaus EC, Karjalainen J et al.

Nat Commun

Inflammatory and infectious upper respiratory diseases (ICD-10: J30-J39), such as diseases of the si...

Pharyngeal disease

Replicated

232365

Participants

N/A

Studies

Details PubMed

GWAS 2022-05-13

Genome-wide integration of genetic and genomic studies of atopic dermatitis: Insights into genetic architecture and pathogenesis.

Chen Y, Chen W

J Invest Dermatol

Atopic dermatitis (AD) is a common heterogeneous, chronic, itching, and inflammatory skin disease. G...

Atopic dermatitis

Replicated

1071010

Participants

N/A

Studies

Details PubMed

GWAS 2021-09-27

Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program.

Mikhaylova AV, McHugh CP et al.

Am J Hum Genet

Many common and rare variants associated with hematologic traits have been discovered through imputa...

White blood cell count

Replicated

260928

Participants

N/A

Studies

Details PubMed

GWAS 2021-08-26

Uniting biobank resources reveals novel genetic pathways modulating susceptibility for atopic dermatitis.

Sliz E, Huilaja L et al.

J Allergy Clin Immunol

Atopic dermatitis (AD) is a common chronic inflammatory skin disease with high heritability. Previou...

Atopic dermatitis

796661

Participants

N/A

Studies

Details PubMed

GWAS 2021-07-13

Novel Role for Caspase Recruitment Domain Family Member 14 and its Genetic Variant rs11652075 in Skin Filaggrin Homeostasis.

DeVore SB, Stevens ML et al.

J Allergy Clin Immunol

Low epidermal filaggrin (FLG) is a risk factor for atopic dermatitis (AD) and allergic comorbidity. ...

Lesional skin FLG expression levels in childhood atopic dermatitis

235

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Integration of GWAS, QTLs and keratinocyte functional assays reveals molecular mechanisms of atopic dermatitis.

Oliva M, Sarkar MK et al.

Nat Commun

Atopic dermatitis

2025-04-01

A genome-wide cross-trait analysis identifying shared genetic basis and causal relationships between Hunner-type interstitial cystitis and autoimmune diseases in East Asian populations.

Lyu X, Peng L et al.

Front Immunol

Hunner-type interstitial cystitis or atopic dermatitis (MTAG)

2024-11-15

Joint genotype and ancestry analysis identify novel loci associated with atopic dermatitis in African American population.

Gautam Y, Satish L et al.

HGG Adv

Atopic dermatitis

2024-09-07

Identifying atopic dermatitis risk loci in 1,094,060 individuals with sub analysis of disease severity and onset.

Pasanen A, Sliz E et al.

J Invest Dermatol

Atopic dermatitis

2024-04-23

Genome-wide Association Study of Susceptibility Loci for Self-Reported Atopic Dermatitis and Allergic Rhinitis in the Korean Population.

Kim JW, Kim MJ et al.

Ann Dermatol

Allergic disease

2024-04-01

The genome-wide association study of serum IgE levels demonstrated the shared genetic background in allergic diseases.

Lu HF, Chou CH et al.

Clin Immunol

Serum IgE levels

2024-01-08

European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.

Budu-Aggrey A, Kilanowski A et al.

Nat Commun

Atopic dermatitis

2023-10-04

Inflammatory and infectious upper respiratory diseases associate with 41 genomic loci and type 2 inflammation.

Saarentaus EC, Karjalainen J et al.

Nat Commun

Pharyngeal disease

2023-01-18

Genome-wide integration of genetic and genomic studies of atopic dermatitis: Insights into genetic architecture and pathogenesis.

Chen Y, Chen W

J Invest Dermatol

Atopic dermatitis

2022-05-13

Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program.

Mikhaylova AV, McHugh CP et al.

Am J Hum Genet

White blood cell count

2021-09-27

Uniting biobank resources reveals novel genetic pathways modulating susceptibility for atopic dermatitis.

Sliz E, Huilaja L et al.

J Allergy Clin Immunol

Atopic dermatitis

2021-08-26

Novel Role for Caspase Recruitment Domain Family Member 14 and its Genetic Variant rs11652075 in Skin Filaggrin Homeostasis.

DeVore SB, Stevens ML et al.

J Allergy Clin Immunol

Lesional skin FLG expression levels in childhood atopic dermatitis

2021-07-13