Active: Biol Psychiatry Clear all

GWAS 2023-12-21

Uncommon protein-coding variants associated with suicide attempt in a diverse sample of US Army soldiers.

Wilkerson MD, Hupalo D et al.

Biol Psychiatry

Suicide is a societal and public health concern of global scale. Identifying genetic risk factors fo...

Suicide attempt

13549

Participants

N/A

Studies

Details PubMed

GWAS 2023-10-21

A Protective Role of Low Polygenic Risk Score in Healthy Individuals Carrying Attention-Deficit/Hyperactivity Disorder-Associated Copy Number Variations.

Chang X, Qu H et al.

Biol Psychiatry

Previous studies have implicated both rare copy number variations (CNVs) and common variants in liab...

Attention deficit hyperactivity disorder

4800

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-28

The Genetic Architecture of Amygdala Nuclei.

Mufford MS, van der Meer D et al.

Biol Psychiatry

Whereas genetic variants influencing total amygdala volume have been identified, the genetic archite...

Basal nucleus volume

31690

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-02

Genome-wide survival study identifies PARL as a novel locus for clinical progression and neurodegeneration in Alzheimer's disease.

Chen SD, Zhang W et al.

Biol Psychiatry

Variability exists in the trajectories of Alzheimer's disease (AD). We aimed to identify genetic mod...

Alzheimer's disease dementia (time to event)

Replicated

212975

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-09

Metabolomic Investigation of Major Depressive Disorder Identifies a Potentially Causal Association With Polyunsaturated Fatty Acids.

Davyson E, Shen X et al.

Biol Psychiatry

Metabolic differences have been reported between individuals with and without major depressive disor...

Docosahexaenoic acid levels (UKB data field 23450)

88268

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-02

Genome-wide Association Study points to novel locus for Gilles de la Tourette Syndrome.

Tsetsos F, Topaloudi A et al.

Biol Psychiatry

Tourette syndrome (TS) is a childhood-onset neurodevelopmental disorder of complex genetic architect...

Tourette syndrome

19698

Participants

N/A

Studies

Details PubMed

GWAS 2022-08-05

Sex-Specific Genetic and Transcriptomic Liability to Neuroticism.

Wendt FR, Pathak GA et al.

Biol Psychiatry

The presentation, etiology, and relative risk of psychiatric disorders are strongly influenced by bi...

Neuroticism

129229

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-14

Genome-wide Association Study Shows That Executive Functioning Is Influenced by GABAergic Processes and Is a Neurocognitive Genetic Correlate of Psychiatric Disorders.

Hatoum AS, Morrison CL et al.

Biol Psychiatry

Deficits in executive functions (EFs), cognitive processes that control goal-directed behaviors, are...

Common executive function

427037

Participants

N/A

Studies

Details PubMed

GWAS 2022-02-11

Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology.

van der Meer D, Shadrin AA et al.

Biol Psychiatry

Schizophrenia is a complex polygenic disorder with subtle, distributed abnormalities in brain morpho...

Brain morphology (MOSTest)

33735

Participants

N/A

Studies

Details PubMed

GWAS 2021-11-02

The Australian Genetics of Depression Study: New Risk Loci and Dissecting Heterogeneity Between Subtypes.

Mitchell BL, Campos AI et al.

Biol Psychiatry

Major depressive disorder (MDD) is a common and highly heterogeneous psychiatric disorder, but littl...

Depression

833555

Participants

N/A

Studies

Details PubMed

GWAS 2021-09-28

Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information.

Maihofer AX, Choi KW et al.

Biol Psychiatry

Posttraumatic stress disorder (PTSD) is heritable and a potential consequence of exposure to traumat...

Post-traumatic stress disorder

182199

Participants

N/A

Studies

Details PubMed

GWAS 2021-09-09

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors.

Mullins N, Kang J et al.

Biol Psychiatry

Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more f...

Suicide attempt

Replicated

959191

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Uncommon protein-coding variants associated with suicide attempt in a diverse sample of US Army soldiers.

Wilkerson MD, Hupalo D et al.

Biol Psychiatry

Suicide attempt

2023-12-21

A Protective Role of Low Polygenic Risk Score in Healthy Individuals Carrying Attention-Deficit/Hyperactivity Disorder-Associated Copy Number Variations.

Chang X, Qu H et al.

Biol Psychiatry

Attention deficit hyperactivity disorder

2023-10-21

The Genetic Architecture of Amygdala Nuclei.

Mufford MS, van der Meer D et al.

Biol Psychiatry

Basal nucleus volume

2023-06-28

Genome-wide survival study identifies PARL as a novel locus for clinical progression and neurodegeneration in Alzheimer's disease.

Chen SD, Zhang W et al.

Biol Psychiatry

Alzheimer's disease dementia (time to event)

2023-03-02

Metabolomic Investigation of Major Depressive Disorder Identifies a Potentially Causal Association With Polyunsaturated Fatty Acids.

Davyson E, Shen X et al.

Biol Psychiatry

Docosahexaenoic acid levels (UKB data field 23450)

2023-02-09

Genome-wide Association Study points to novel locus for Gilles de la Tourette Syndrome.

Tsetsos F, Topaloudi A et al.

Biol Psychiatry

Tourette syndrome

2023-02-02

Sex-Specific Genetic and Transcriptomic Liability to Neuroticism.

Wendt FR, Pathak GA et al.

Biol Psychiatry

Neuroticism

2022-08-05

Genome-wide Association Study Shows That Executive Functioning Is Influenced by GABAergic Processes and Is a Neurocognitive Genetic Correlate of Psychiatric Disorders.

Hatoum AS, Morrison CL et al.

Biol Psychiatry

Common executive function

2022-07-14

Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology.

van der Meer D, Shadrin AA et al.

Biol Psychiatry

Brain morphology (MOSTest)

2022-02-11

The Australian Genetics of Depression Study: New Risk Loci and Dissecting Heterogeneity Between Subtypes.

Mitchell BL, Campos AI et al.

Biol Psychiatry

Depression

2021-11-02

Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information.

Maihofer AX, Choi KW et al.

Biol Psychiatry

Post-traumatic stress disorder

2021-09-28

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors.

Mullins N, Kang J et al.

Biol Psychiatry

Suicide attempt

2021-09-09