Health & Traits Publications

Eektimmerman F, Swen JJ et al.

Clin Pharmacol Ther

Hepatotoxicity is a serious adverse drug reaction related to methotrexate (MTX). However, the cause ...

Methotrexate-induced liver injury in rheumatoid arthritis

Nakamura R, Arakawa N et al.

Hepatol Res

Aim: Drug-induced liver injury (DILI) is a severe and life-threatening immune-mediated adverse effec...

Drug-induced liver injury

Nicoletti P, Devarbhavi H et al.

Clin Pharmacol Ther

Drug-induced liver injury (DILI) is a complication of treatment with antituberculosis (TB) drugs, es...

Drug-induced liver injury (isoniazid-containing anti-tuberculosis drugs)

Suvichapanich S, Wattanapokayakit S et al.

Antimicrob Agents Chemother

Antituberculosis drug-induced liver injury (ATDILI) is a common side effect leading to tuberculosis ...

Liver injury in anti-tuberculosis drug treatment

Nicoletti P, Barrett S et al.

Clin Pharmacol Ther

Carbamazepine (CBZ) causes life-threating T-cell-mediated hypersensitivity reactions, including seri...

Carbamazepine-induced liver injury

Nicoletti P, Aithal GP et al.

Clin Pharmacol Ther

Some patients prescribed flucloxacillin (~ 0.01%) develop drug-induced liver injury (DILI). HLA-B*57...

Drug-induced liver injury (flucloxacillin)

Cirulli ET, Nicoletti P et al.

Gastroenterology

Background & aims: We performed genetic analyses of a multiethnic cohort of patients with idiosy...

Drug-induced liver injury

Kowalec K, Wright GEB et al.

Nat Genet

Multiple sclerosis (MS) is a disease of the central nervous system treated with disease-modifying th...

Drug-induced liver injury in interferon-beta-treated multiple sclerosis

Carr DF, Bourgeois S et al.

J Antimicrob Chemother

The antiretroviral nevirapine is associated with hypersensitivity reactions in 6%-10% of patients, i...

Nevirapine-induced hypersensitivity in HIV (drug-induced liver injury)

Nicoletti P, Aithal GP et al.

Gastroenterology

Background & aims: We performed a genome-wide association study (GWAS) to identify genetic risk ...

Drug-induced liver injury (terbinafine)

Petros Z, Lee MM et al.

BMC Genomics

Drug-induced liver injury (DILI) is a well-recognized adverse event of anti tuberculosis drugs (ATD)...

Liver injury in anti-tuberculosis drug treatment

Nicoletti P, Werk AN et al.

Pharmacogenet Genomics

Objective: Flupirtine is a nonopioid analgesic with regulatory approval in a number of European coun...

Drug-induced liver injury