Active: Eur Respir J Clear all

GWAS 2025-07-17

Genomics of chronic dry cough unravels neurological pathways.

Coley K, John C et al.

Eur Respir J

Chronic dry cough is a symptom of common lung conditions, can occur as a side-effect of angiotensin-...

Chronic dry cough or cough in response to angiotensin-converting enzyme inhibitor drugs

180380

Participants

N/A

Studies

Details PubMed

GWAS 2025-06-26

Genetic associations between Serotonin Receptor 1F (HTR1F) regulatory variation and sleep apnea in non-obese individuals: Insights from GWAS and eQTL analyses.

Strausz S, Broberg M et al.

Eur Respir J

Sleep apnoea is a common sleep disorder affecting at least 10% of the population. It is caused by la...

Sleep apnea with BMI < 30

463876

Participants

N/A

Studies

Details PubMed

GWAS 2023-12-22

Genome Wide Association Study of Preserved Ratio Impaired Spirometry (PRISm).

Higbee DH, Lirio A et al.

Eur Respir J

Preserved ratio impaired spirometry (PRISm) is defined as a forced expiratory volume in 1 s (FEV1) &...

Preserved ratio impaired spirometry

Replicated

342676

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-01

Genome-wide association study of chronic sputum production implicates loci involved in mucus production and infection.

Packer RJ, Shrine N et al.

Eur Respir J

Chronic sputum production impacts on quality of life and is a feature of many respiratory diseases. ...

Chronic sputum production

Replicated

77789

Participants

N/A

Studies

Details PubMed

GWAS 2022-08-11

Zinc finger protein 33B demonstrates sex-interaction with atopy-related markers in childhood asthma.

Lee S, Prokopenko D et al.

Eur Respir J

Sex differences related to immune responses can influence atopic manifestations in childhood asthma....

Atopy in childhood asthma x sex interaction

3519

Participants

N/A

Studies

Details PubMed

GWAS 2021-03-25

A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic etiology with obesity.

Zhu Z, Li J et al.

Eur Respir J

Lung function is a heritable complex phenotype with obesity being one of its important risk factors....

Lung function (FEV1)

Replicated

100285

Participants

N/A

Studies

Details PubMed

GWAS 2021-02-04

Genome-wide association study in patients with pulmonary Mycobacterium avium complex disease.

Namkoong H, Omae Y et al.

Eur Respir J

Rationale: Nontuberculous mycobacteria (NTM) are environmental mycobacteria that can cause a chronic...

Pulmonary mycobacterium avium complex disease

Replicated

5127

Participants

N/A

Studies

Details PubMed

GWAS 2020-12-10

Genome-wide association study of asthma exacerbations despite inhaled corticosteroids use.

Hernandez-Pacheco N, Vijverberg SJ et al.

Eur Respir J

Rationale: Substantial variability in response to asthma treatment with inhaled corticosteroids (ICS...

Asthma exacerbations in inhaled corticosteroid treatment

Replicated

3219

Participants

N/A

Studies

Details PubMed

GWAS 2020-11-26

Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health.

Strausz S, Ruotsalainen S et al.

Eur Respir J

There is currently limited understanding of the genetic aetiology of obstructive sleep apnoea (OSA)....

Obstructive sleep apnea

Replicated

1177519

Participants

N/A

Studies

Details PubMed

GWAS 2020-10-22

A genome-wide association study of severe asthma exacerbations in Latino children and adolescents.

Yan Q, Forno E et al.

Eur Respir J

Severe asthma exacerbations are a major cause of school absences and healthcare costs in children, p...

Severe exacerbations in childhood asthma

4010

Participants

N/A

Studies

Details PubMed

GWAS 2019-10-17

Shared Genetics of Asthma and Mental Health Disorders: A Large-Scale Genome-Wide Cross-Trait Analysis.

Zhu Z, Zhu X et al.

Eur Respir J

Epidemiological studies demonstrate an association between asthma and mental health disorders, altho...

Asthma

Replicated

536769

Participants

N/A

Studies

Details PubMed

GWAS 2019-09-19

The Pharmacogenomics of Inhaled Corticosteroids and Lung Function Decline in COPD.

Obeidat M, Faiz A et al.

Eur Respir J

Inhaled corticosteroids (ICS) are widely prescribed for patients with chronic obstructive pulmonary ...

FEV1 decline rate x corticosteroid treatment interaction in chronic obstructive pulmonary disease

Replicated

1001

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genomics of chronic dry cough unravels neurological pathways.

Coley K, John C et al.

Eur Respir J

Chronic dry cough or cough in response to angiotensin-converting enzyme inhibitor drugs

2025-07-17

Genetic associations between Serotonin Receptor 1F (HTR1F) regulatory variation and sleep apnea in non-obese individuals: Insights from GWAS and eQTL analyses.

Strausz S, Broberg M et al.

Eur Respir J

Sleep apnea with BMI < 30

2025-06-26

Genome Wide Association Study of Preserved Ratio Impaired Spirometry (PRISm).

Higbee DH, Lirio A et al.

Eur Respir J

Preserved ratio impaired spirometry

2023-12-22

Genome-wide association study of chronic sputum production implicates loci involved in mucus production and infection.

Packer RJ, Shrine N et al.

Eur Respir J

Chronic sputum production

2023-06-01

Zinc finger protein 33B demonstrates sex-interaction with atopy-related markers in childhood asthma.

Lee S, Prokopenko D et al.

Eur Respir J

Atopy in childhood asthma x sex interaction

2022-08-11

A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic etiology with obesity.

Zhu Z, Li J et al.

Eur Respir J

Lung function (FEV1)

2021-03-25

Genome-wide association study in patients with pulmonary Mycobacterium avium complex disease.

Namkoong H, Omae Y et al.

Eur Respir J

Pulmonary mycobacterium avium complex disease

2021-02-04

Genome-wide association study of asthma exacerbations despite inhaled corticosteroids use.

Hernandez-Pacheco N, Vijverberg SJ et al.

Eur Respir J

Asthma exacerbations in inhaled corticosteroid treatment

2020-12-10

Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health.

Strausz S, Ruotsalainen S et al.

Eur Respir J

Obstructive sleep apnea

2020-11-26

A genome-wide association study of severe asthma exacerbations in Latino children and adolescents.

Yan Q, Forno E et al.

Eur Respir J

Severe exacerbations in childhood asthma

2020-10-22

Shared Genetics of Asthma and Mental Health Disorders: A Large-Scale Genome-Wide Cross-Trait Analysis.

Zhu Z, Zhu X et al.

Eur Respir J

Asthma

2019-10-17

The Pharmacogenomics of Inhaled Corticosteroids and Lung Function Decline in COPD.

Obeidat M, Faiz A et al.

Eur Respir J

FEV1 decline rate x corticosteroid treatment interaction in chronic obstructive pulmonary disease

2019-09-19

Health & Traits Publications

Genomics of chronic dry cough unravels neurological pathways.

Genetic associations between Serotonin Receptor 1F (<i>HTR1F</i>) regulatory variation and sleep apnea in non-obese individuals: Insights from GWAS and eQTL analyses.

Genome Wide Association Study of Preserved Ratio Impaired Spirometry (PRISm).

Genome-wide association study of chronic sputum production implicates loci involved in mucus production and infection.

Zinc finger protein 33B demonstrates sex-interaction with atopy-related markers in childhood asthma.

A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic etiology with obesity.

Genome-wide association study in patients with pulmonary <i>Mycobacterium avium</i> complex disease.

Genome-wide association study of asthma exacerbations despite inhaled corticosteroids use.

Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health.

A genome-wide association study of severe asthma exacerbations in Latino children and adolescents.

Shared Genetics of Asthma and Mental Health Disorders: A Large-Scale Genome-Wide Cross-Trait Analysis.

The Pharmacogenomics of Inhaled Corticosteroids and Lung Function Decline in COPD.